Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1' and Ligand = 'BDBM50435507'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50435507 (CHEMBL2392481) Show SMILES N#CCCO[C@H]1CC[C@@H](CC1)n1nnc2cnc3[nH]ccc3c12 |r,wU:5.4,wD:8.11,(24.44,-37.17,;23.09,-36.44,;21.74,-35.71,;20.43,-36.51,;19.08,-35.78,;17.77,-36.58,;17.81,-38.12,;16.5,-38.93,;15.15,-38.19,;15.1,-36.66,;16.41,-35.85,;13.84,-39,;12.32,-38.85,;11.71,-40.25,;12.85,-41.27,;12.85,-42.81,;14.18,-43.58,;15.52,-42.8,;16.99,-43.27,;17.89,-42.01,;16.98,-40.77,;15.51,-41.26,;14.17,-40.49,)| Show InChI InChI=1S/C16H18N6O/c17-7-1-9-23-12-4-2-11(3-5-12)22-15-13-6-8-18-16(13)19-10-14(15)20-21-22/h6,8,10-12H,1-5,9H2,(H,18,19)/t11-,12-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>3.76E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Argenta Discovery Ltd. Curated by ChEMBL					Assay Description Inhibition of JAK1 (unknown origin)				Bioorg Med Chem Lett 23: 3592-8 (2013) Article DOI: 10.1016/j.bmcl.2013.04.018 BindingDB Entry DOI: 10.7270/Q2GH9KB2
					More data for this Ligand-Target Pair