Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1' and Ligand = 'BDBM50435517'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50435517 (CHEMBL2392482) Show SMILES CC(C)(C)OC(=O)N[C@H]1CC[C@@H](CC1)n1nnc2cnc3[nH]ccc3c12 |r,wU:8.7,wD:11.14,(38.37,-38.93,;38.33,-37.4,;39.64,-36.59,;39.65,-38.16,;36.97,-36.66,;35.66,-37.47,;35.7,-39.01,;34.31,-36.73,;33,-37.54,;33.04,-39.08,;31.73,-39.88,;30.37,-39.15,;30.32,-37.61,;31.64,-36.8,;29.07,-39.95,;27.55,-39.8,;26.93,-41.21,;28.08,-42.22,;28.08,-43.77,;29.41,-44.54,;30.75,-43.76,;32.22,-44.23,;33.12,-42.97,;32.2,-41.73,;30.74,-42.22,;29.4,-41.45,)| Show InChI InChI=1S/C18H24N6O2/c1-18(2,3)26-17(25)21-11-4-6-12(7-5-11)24-15-13-8-9-19-16(13)20-10-14(15)22-23-24/h8-12H,4-7H2,1-3H3,(H,19,20)(H,21,25)/t11-,12-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Argenta Discovery Ltd. Curated by ChEMBL					Assay Description Inhibition of JAK1 (unknown origin)				Bioorg Med Chem Lett 23: 3592-8 (2013) Article DOI: 10.1016/j.bmcl.2013.04.018 BindingDB Entry DOI: 10.7270/Q2GH9KB2
					More data for this Ligand-Target Pair