Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1' and Ligand = 'BDBM50527910'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50527910 (CHEMBL4517840) Show SMILES CN(C)CC(=O)Nc1cccc2c(c[nH]c12)-c1nc(NC(=O)C2CC2)ncc1C Show InChI InChI=1S/C21H24N6O2/c1-12-9-23-21(26-20(29)13-7-8-13)25-18(12)15-10-22-19-14(15)5-4-6-16(19)24-17(28)11-27(2)3/h4-6,9-10,13,22H,7-8,11H2,1-3H3,(H,24,28)(H,23,25,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged JAK1 (866 to 1154 residues) expressed in insect cells using FITC-labeled C6-KKHTDDGYMPMSPGVA-NH...				J Med Chem 63: 4517-4527 (2020) Article DOI: 10.1021/acs.jmedchem.9b01392 BindingDB Entry DOI: 10.7270/Q21V5JDF
					More data for this Ligand-Target Pair