Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1' and Ligand = 'BDBM521947'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM521947 (N-[3-[6-(difluoromethoxy)-2- methyl-3,4-dihydro-2H...) Show SMILES CC1CNc2cc(OC(F)F)c(cc2S1)-c1n[nH]cc1NC(=O)c1cnn2cccnc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5S1D
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM521947 (N-[3-[6-(difluoromethoxy)-2- methyl-3,4-dihydro-2H...) Show SMILES CC1CNc2cc(OC(F)F)c(cc2S1)-c1n[nH]cc1NC(=O)c1cnn2cccnc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5S1D
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM521947 (N-[3-[6-(difluoromethoxy)-2- methyl-3,4-dihydro-2H...) Show SMILES CC1CNc2cc(OC(F)F)c(cc2S1)-c1n[nH]cc1NC(=O)c1cnn2cccnc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...				Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5S1D
					More data for this Ligand-Target Pair