Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM466346 ((8S)-N-[(2S)-2- cyclohexyl-2- hydroxy-ethyl]-5- (7...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a |
Leo Pharma A/S US Patent | Assay Description Human baculovirus-expressed JAK1, 2, 3 and TYK2 were purchased from Carna Biosciences, Inc. All four purified enzymes contain only the catalytic doma... | US Patent US10799507 (2020) BindingDB Entry DOI: 10.7270/Q2VM4GBC | |||||||||||
More data for this Ligand-Target Pair |