Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50003603'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50003603 (CHEMBL3234879) Show SMILES Cc1cccc(Nc2sc(cc2C(N)=O)-c2cccc(F)c2F)n1 Show InChI InChI=1S/C17H13F2N3OS/c1-9-4-2-7-14(21-9)22-17-11(16(20)23)8-13(24-17)10-5-3-6-12(18)15(10)19/h2-8H,1H3,(H2,20,23)(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Merck& Co. Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin)				Bioorg Med Chem Lett 24: 1968-73 (2014) Article DOI: 10.1016/j.bmcl.2014.02.064 BindingDB Entry DOI: 10.7270/Q2CF9RM3
					More data for this Ligand-Target Pair