Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50045563'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50045563 (CHEMBL3314279) Show SMILES CCOP(=O)(CCn1cc(nn1)-c1ccc(cc1)-c1nc(c([nH]1)-c1cc[nH]c(=O)c1)-c1ccc(F)cc1)OCC Show InChI InChI=1S/C28H28FN6O4P/c1-3-38-40(37,39-4-2)16-15-35-18-24(33-34-35)19-5-7-21(8-6-19)28-31-26(20-9-11-23(29)12-10-20)27(32-28)22-13-14-30-25(36)17-22/h5-14,17-18H,3-4,15-16H2,1-2H3,(H,30,36)(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Syncom B.V. Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin) by radiometric assay				Bioorg Med Chem Lett 24: 3412-8 (2014) Article DOI: 10.1016/j.bmcl.2014.05.080 BindingDB Entry DOI: 10.7270/Q2D50PKZ
					More data for this Ligand-Target Pair