Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50193989'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50193989 (CHEMBL221976 | N-((S)-1-(4-fluorophenyl)ethyl)-2-(...) Show SMILES C[C@H](Nc1ccnc(n1)-n1cnc2ccncc12)c1ccc(F)cc1 Show InChI InChI=1S/C18H15FN6/c1-12(13-2-4-14(19)5-3-13)23-17-7-9-21-18(24-17)25-11-22-15-6-8-20-10-16(15)25/h2-12H,1H3,(H,21,23,24)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of JAK2				Bioorg Med Chem Lett 16: 5633-8 (2006) Article DOI: 10.1016/j.bmcl.2006.08.022 BindingDB Entry DOI: 10.7270/Q2J1040K
					More data for this Ligand-Target Pair