Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50194002'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50194002 (CHEMBL376885 | N-(2-chlorophenyl)-2-(3H-imidazo[4,...) Show SMILES CN1CCN(CC1)c1cc(Nc2ccccc2Cl)nc(n1)-n1cnc2ccncc12 Show InChI InChI=1S/C21H21ClN8/c1-28-8-10-29(11-9-28)20-12-19(25-16-5-3-2-4-15(16)22)26-21(27-20)30-14-24-17-6-7-23-13-18(17)30/h2-7,12-14H,8-11H2,1H3,(H,25,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	113	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of JAK2				Bioorg Med Chem Lett 16: 5633-8 (2006) Article DOI: 10.1016/j.bmcl.2006.08.022 BindingDB Entry DOI: 10.7270/Q2J1040K
					More data for this Ligand-Target Pair