Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50194006'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50194006 (6-(3-(dimethylamino)phenyl)-2-(3H-imidazo[4,5-c]py...) Show SMILES C[C@H](Nc1cc(nc(n1)-n1cnc2ccncc12)-c1cccc(c1)N(C)C)c1ccccc1 Show InChI InChI=1S/C26H25N7/c1-18(19-8-5-4-6-9-19)29-25-15-23(20-10-7-11-21(14-20)32(2)3)30-26(31-25)33-17-28-22-12-13-27-16-24(22)33/h4-18H,1-3H3,(H,29,30,31)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	167	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of JAK2				Bioorg Med Chem Lett 16: 5633-8 (2006) Article DOI: 10.1016/j.bmcl.2006.08.022 BindingDB Entry DOI: 10.7270/Q2J1040K
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