Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50194007'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50194007 (3-(4-(2,6-difluorophenoxy)-6-(4-methylpiperazin-1-...) Show SMILES CN1CCN(CC1)c1cc(Oc2c(F)cccc2F)nc(n1)-n1cnc2ccncc12 Show InChI InChI=1S/C21H19F2N7O/c1-28-7-9-29(10-8-28)18-11-19(31-20-14(22)3-2-4-15(20)23)27-21(26-18)30-13-25-16-5-6-24-12-17(16)30/h2-6,11-13H,7-10H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of JAK2				Bioorg Med Chem Lett 16: 5633-8 (2006) Article DOI: 10.1016/j.bmcl.2006.08.022 BindingDB Entry DOI: 10.7270/Q2J1040K
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