Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50201809'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50201809 (CHEMBL3903955) Show SMILES Cc1cnc(Nc2ccc(cc2)N2CCOCC2)nc1-c1cc2cc(COCC(F)(F)F)ccc2o1 Show InChI InChI=1S/C26H25F3N4O3/c1-17-14-30-25(31-20-3-5-21(6-4-20)33-8-10-34-11-9-33)32-24(17)23-13-19-12-18(2-7-22(19)36-23)15-35-16-26(27,28)29/h2-7,12-14H,8-11,15-16H2,1H3,(H,30,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of GST-tagged recombinant human JAK2 expressed in baculovirus using TK-substrate-biotin as substrate preincubated for 5 mins followed by s...				Bioorg Med Chem 25: 75-83 (2017) Article DOI: 10.1016/j.bmc.2016.10.011 BindingDB Entry DOI: 10.7270/Q21Z46CH
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