Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50311031'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50311031 (CHEMBL1078933 | N-(cyanomethyl)-4-(2-(4-((4-ethylp...) Show SMILES CCN1CCN(Cc2ccc(Nc3nccc(n3)-c3ccc(cc3)C(=O)NCC#N)cc2)CC1 Show InChI InChI=1S/C26H29N7O/c1-2-32-15-17-33(18-16-32)19-20-3-9-23(10-4-20)30-26-29-13-11-24(31-26)21-5-7-22(8-6-21)25(34)28-14-12-27/h3-11,13H,2,14-19H2,1H3,(H,28,34)(H,29,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Cytopia Research Pty Ltd Curated by ChEMBL					Assay Description Inhibition of GST-tagged JAK2 kinase				Bioorg Med Chem Lett 19: 5887-92 (2009) Article DOI: 10.1016/j.bmcl.2009.08.071 BindingDB Entry DOI: 10.7270/Q2C24WKM
					More data for this Ligand-Target Pair