Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50331812'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50331812 (2-(3,3-difluoropyrrolidin-1-yl)-3-(4-fluorophenyl)...) Show SMILES Fc1ccc(cc1)-c1cc2c(cc[nH]c2=O)nc1N1CCC(F)(F)C1 Show InChI InChI=1S/C18H14F3N3O/c19-12-3-1-11(2-4-12)13-9-14-15(5-7-22-17(14)25)23-16(13)24-8-6-18(20,21)10-24/h1-5,7,9H,6,8,10H2,(H,22,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.18E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck& Co. Curated by ChEMBL					Assay Description Inhibition of JAK2 in cell-free system				Bioorg Med Chem Lett 20: 7421-5 (2010) Article DOI: 10.1016/j.bmcl.2010.10.031 BindingDB Entry DOI: 10.7270/Q2SQ90MG
					More data for this Ligand-Target Pair