Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50537335'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50537335 (CHEMBL4559204) Show SMILES Nc1n[nH]c2ccc(NC(=O)c3cc(Cl)ccc3Cl)cc12 Show InChI InChI=1S/C14H10Cl2N4O/c15-7-1-3-11(16)9(5-7)14(21)18-8-2-4-12-10(6-8)13(17)20-19-12/h1-6H,(H,18,21)(H3,17,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Hungarian Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin) after 1 hr FRET-based Z'-Lyte assay				Bioorg Med Chem 27: 1497-1508 (2019) Article DOI: 10.1016/j.bmc.2019.02.029 BindingDB Entry DOI: 10.7270/Q2B27ZSZ
					More data for this Ligand-Target Pair