Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50544784'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50544784 (CHEMBL4641006) Show SMILES [H][C@@]12CN(C(=O)[C@]1(C#N)C1CC1)c1ccnc(Nc3cccc(CCCNC(=O)COC2)n3)c1 |r| Show InChI InChI=1S/C24H26N6O3/c25-15-24(16-6-7-16)17-12-30(23(24)32)19-8-10-26-21(11-19)29-20-5-1-3-18(28-20)4-2-9-27-22(31)14-33-13-17/h1,3,5,8,10-11,16-17H,2,4,6-7,9,12-14H2,(H,27,31)(H,26,28,29)/t17-,24+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126963 BindingDB Entry DOI: 10.7270/Q24X5CCJ
					More data for this Ligand-Target Pair