Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2 [532-1132]' and Ligand = 'BDBM505113'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 [532-1132] (Homo sapiens (Human))	BDBM505113 (US11066406, Ex. 7) Show SMILES CC(C)(CNC(=O)Cc1nc2cnc3[nH]ccc3c2n1C1CCC(CC#N)CC1)C#N |(12.86,2.75,;12.09,1.42,;11.32,.08,;10.75,2.19,;9.42,1.42,;8.08,2.19,;8.08,3.73,;6.75,1.42,;5.42,2.19,;5.26,3.72,;3.75,4.04,;2.98,5.37,;1.44,5.37,;.67,4.04,;-.84,3.72,;-1,2.19,;.41,1.56,;1.44,2.71,;2.98,2.71,;4.01,1.56,;3.69,.06,;4.83,-.98,;4.51,-2.48,;3.05,-2.96,;2.73,-4.46,;1.26,-4.94,;-.2,-5.42,;1.91,-1.93,;2.23,-.42,;13.42,.65,;14.75,-.12,)| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Substrate (NH2-KGGEEEEYFELVKK-CO2), internal standard peptide (NH2-SWGAIETDKEYYTVKD-CO2) and product peptide (for standard curve only) (NH2-KGGEEEEY-...				Citation and Details BindingDB Entry DOI: 10.7270/Q2571G4J
					More data for this Ligand-Target Pair