Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2 [826-1132]' and Ligand = 'BDBM458952'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 [826-1132] (Homo sapiens (Human))	BDBM458952 (US10759793, Example 96) Show SMILES COCCOc1cc(N[C@@H]2CCCN(C2)C(=O)CO)nc(n1)-c1cnn2ccccc12 Show InChI InChI=1S/C21H26N6O4/c1-30-9-10-31-19-11-18(23-15-5-4-7-26(13-15)20(29)14-28)24-21(25-19)16-12-22-27-8-3-2-6-17(16)27/h2-3,6,8,11-12,15,28H,4-5,7,9-10,13-14H2,1H3,(H,23,24,25)/t15-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Almirall, S.A. US Patent					Assay Description The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...				US Patent US10759793 (2020) BindingDB Entry DOI: 10.7270/Q2QC06MG
					More data for this Ligand-Target Pair