Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM107140'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM107140 (US8592415, 25) Show SMILES CSCC(=O)Nc1cccc(c1)-c1cnc2ccccc2n1 Show InChI InChI=1S/C17H15N3OS/c1-22-11-17(21)19-13-6-4-5-12(9-13)16-10-18-14-7-2-3-8-15(14)20-16/h2-10H,11H2,1H3,(H,19,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Reaction Biology Corp.; Synerga Limited US Patent					Assay Description In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2.				US Patent US8592415 (2013) BindingDB Entry DOI: 10.7270/Q218354P
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