Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM286373'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM286373 (US9518052, Example 155) Show SMILES CCc1cc(O)c(F)cc1-c1cc(N)c(C=N)c(NCc2ccccc2N(C)S(C)(=O)=O)n1 Show InChI InChI=1S/C23H26FN5O3S/c1-4-14-9-22(30)18(24)10-16(14)20-11-19(26)17(12-25)23(28-20)27-13-15-7-5-6-8-21(15)29(2)33(3,31)32/h5-12,25,30H,4,13H2,1-3H3,(H3,26,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15.5	n/a	n/a	n/a	n/a	7.4	25
Pfizer Inc. US Patent					Assay Description Test article was solubilized in dimethyl sulfoxide (DMSO) to a stock concentration of 30 mM. An 11-point half log dilution series was created in DMSO...				US Patent US9518052 (2016) BindingDB Entry DOI: 10.7270/Q2736SZ5
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