Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM475637'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM475637 (US10851102, Example 30 | US11339160, Ex No. 30) Show SMILES Oc1ccc(cc1)-c1cc(OC2CCN(CC2)C(=O)C=C)c2cncn2c1 Show InChI InChI=1S/C21H21N3O3/c1-2-21(26)23-9-7-18(8-10-23)27-20-11-16(13-24-14-22-12-19(20)24)15-3-5-17(25)6-4-15/h2-6,11-14,18,25H,1,7-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CF9T9W
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM475637 (US10851102, Example 30 | US11339160, Ex No. 30) Show SMILES Oc1ccc(cc1)-c1cc(OC2CCN(CC2)C(=O)C=C)c2cncn2c1 Show InChI InChI=1S/C21H21N3O3/c1-2-21(26)23-9-7-18(8-10-23)27-20-11-16(13-24-14-22-12-19(20)24)15-3-5-17(25)6-4-15/h2-6,11-14,18,25H,1,7-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Theravance Biopharma R&D IP, LLC US Patent									US Patent US10851102 (2020) BindingDB Entry DOI: 10.7270/Q2N87DV3
					More data for this Ligand-Target Pair