Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM475640'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM475640 (US10851102, Example 33 | US11339160, Ex No. 33) Show SMILES Oc1c(Cl)cc(cc1Cl)-c1cc(OCC2CN(C2)C(=O)C=C)c2cncn2c1 Show InChI InChI=1S/C20H17Cl2N3O3/c1-2-19(26)24-7-12(8-24)10-28-18-5-14(9-25-11-23-6-17(18)25)13-3-15(21)20(27)16(22)4-13/h2-6,9,11-12,27H,1,7-8,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CF9T9W
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM475640 (US10851102, Example 33 | US11339160, Ex No. 33) Show SMILES Oc1c(Cl)cc(cc1Cl)-c1cc(OCC2CN(C2)C(=O)C=C)c2cncn2c1 Show InChI InChI=1S/C20H17Cl2N3O3/c1-2-19(26)24-7-12(8-24)10-28-18-5-14(9-25-11-23-6-17(18)25)13-3-15(21)20(27)16(22)4-13/h2-6,9,11-12,27H,1,7-8,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Theravance Biopharma R&D IP, LLC US Patent									US Patent US10851102 (2020) BindingDB Entry DOI: 10.7270/Q2N87DV3
					More data for this Ligand-Target Pair