Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM50045569'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50045569 (CHEMBL3314284) Show SMILES [K+].Fc1ccc(cc1)-c1nc([nH]c1-c1cc[nH]c(=O)c1)-c1ccc(cc1)-c1nnn[n-]1 Show InChI InChI=1S/C21H14FN7O/c22-16-7-5-12(6-8-16)18-19(15-9-10-23-17(30)11-15)25-20(24-18)13-1-3-14(4-2-13)21-26-28-29-27-21/h1-11H,(H3,23,24,25,26,27,28,29,30)/p-1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	783	n/a	n/a	n/a	n/a	n/a	n/a
Syncom B.V. Curated by ChEMBL					Assay Description Inhibition of JAK3 (unknown origin) by radiometric assay				Bioorg Med Chem Lett 24: 3412-8 (2014) Article DOI: 10.1016/j.bmcl.2014.05.080 BindingDB Entry DOI: 10.7270/Q2D50PKZ
					More data for this Ligand-Target Pair