Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM50109422'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50109422 (CHEMBL3601244) Show SMILES Clc1cnc(Nc2cnoc2)nc1NCc1cccc(NC(=O)C=C)c1 Show InChI InChI=1S/C17H15ClN6O2/c1-2-15(25)22-12-5-3-4-11(6-12)7-19-16-14(18)9-20-17(24-16)23-13-8-21-26-10-13/h2-6,8-10H,1,7H2,(H,22,25)(H2,19,20,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of JAK3 (unknown origin) by Z'-Lyte assay				J Med Chem 58: 6589-606 (2015) Article DOI: 10.1021/acs.jmedchem.5b00710 BindingDB Entry DOI: 10.7270/Q2833TSH
					More data for this Ligand-Target Pair