Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM50193994'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50193994 (4-(2-(3H-imidazo[4,5-c]pyridin-3-yl)-6-((S)-1-phen...) Show SMILES C[C@H](Nc1cc(nc(n1)-n1cnc2ccncc12)-c1ccc(cc1)C#N)c1ccccc1 Show InChI InChI=1S/C25H19N7/c1-17(19-5-3-2-4-6-19)29-24-13-22(20-9-7-18(14-26)8-10-20)30-25(31-24)32-16-28-21-11-12-27-15-23(21)32/h2-13,15-17H,1H3,(H,29,30,31)/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of JAK3				Bioorg Med Chem Lett 16: 5633-8 (2006) Article DOI: 10.1016/j.bmcl.2006.08.022 BindingDB Entry DOI: 10.7270/Q2J1040K
					More data for this Ligand-Target Pair