Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM50194008'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50194008 (3-(4-(furan-3-yl)-6-((S)-1-phenylethylamino)pyrimi...) Show SMILES C[C@H](Nc1cc(nc(n1)-n1cnc2ccc(cc12)C#N)-c1ccoc1)c1ccccc1 Show InChI InChI=1S/C24H18N6O/c1-16(18-5-3-2-4-6-18)27-23-12-21(19-9-10-31-14-19)28-24(29-23)30-15-26-20-8-7-17(13-25)11-22(20)30/h2-12,14-16H,1H3,(H,27,28,29)/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of JAK3				Bioorg Med Chem Lett 16: 5633-8 (2006) Article DOI: 10.1016/j.bmcl.2006.08.022 BindingDB Entry DOI: 10.7270/Q2J1040K
					More data for this Ligand-Target Pair