Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM50201504'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50201504 (CHEMBL233555 | N-(2-(dimethylamino)ethyl)-2-(3H-im...) Show SMILES C[C@H](Nc1nc(nc2n(C)c(cc12)C(=O)NCCN(C)C)-n1cnc2ccncc12)c1ccccc1 Show InChI InChI=1S/C26H29N9O/c1-17(18-8-6-5-7-9-18)30-23-19-14-21(25(36)28-12-13-33(2)3)34(4)24(19)32-26(31-23)35-16-29-20-10-11-27-15-22(20)35/h5-11,14-17H,12-13H2,1-4H3,(H,28,36)(H,30,31,32)/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of JAK3 by kinase-Glo luminescent assay				Bioorg Med Chem Lett 17: 1250-3 (2007) Article DOI: 10.1016/j.bmcl.2006.12.018 BindingDB Entry DOI: 10.7270/Q2H70GMJ
					More data for this Ligand-Target Pair