Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM50201512'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50201512 ((2-(3H-imidazo[4,5-c]pyridin-3-yl)-7-methyl-4-((S)...) Show SMILES C[C@H](Nc1nc(nc2n(C)c(cc12)C(=O)N1CCOCC1)-n1cnc2ccncc12)c1ccccc1 Show InChI InChI=1S/C26H26N8O2/c1-17(18-6-4-3-5-7-18)29-23-19-14-21(25(35)33-10-12-36-13-11-33)32(2)24(19)31-26(30-23)34-16-28-20-8-9-27-15-22(20)34/h3-9,14-17H,10-13H2,1-2H3,(H,29,30,31)/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of JAK3 by kinase-Glo luminescent assay				Bioorg Med Chem Lett 17: 1250-3 (2007) Article DOI: 10.1016/j.bmcl.2006.12.018 BindingDB Entry DOI: 10.7270/Q2H70GMJ
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