Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM50201516'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50201516 (2-(3H-imidazo[4,5-c]pyridin-3-yl)-N-(2-methoxyethy...) Show SMILES COCCNC(=O)c1cc2c(N[C@@H](C)c3ccccc3)nc(nc2n1C)-n1cnc2ccncc12 Show InChI InChI=1S/C25H26N8O2/c1-16(17-7-5-4-6-8-17)29-22-18-13-20(24(34)27-11-12-35-3)32(2)23(18)31-25(30-22)33-15-28-19-9-10-26-14-21(19)33/h4-10,13-16H,11-12H2,1-3H3,(H,27,34)(H,29,30,31)/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of JAK3 by kinase-Glo luminescent assay				Bioorg Med Chem Lett 17: 1250-3 (2007) Article DOI: 10.1016/j.bmcl.2006.12.018 BindingDB Entry DOI: 10.7270/Q2H70GMJ
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