Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM50210177![]() (ONX-0803 | Pacritinib | SB-1518 | SB1518) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase PC cid PC sid PDB UniChem Similars | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description Binding affinity towards rat beta adrenergic receptor from heart membranes. | Citation and Details | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM50210177![]() (ONX-0803 | Pacritinib | SB-1518 | SB1518) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 520 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01851 BindingDB Entry DOI: 10.7270/Q25Q515Z | ||||||||||||
More data for this Ligand-Target Pair |