Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM50384885'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50384885 (CHEMBL2035043) Show SMILES C1OCc2cccc(Nc3nccc(n3)-c3ccc4ccn(C\C=C\1)c4c3)c2 |t:24| Show InChI InChI=1S/C23H20N4O/c1-2-13-28-16-17-4-3-5-20(14-17)25-23-24-10-8-21(26-23)19-7-6-18-9-12-27(11-1)22(18)15-19/h1-10,12,14-15H,11,13,16H2,(H,24,25,26)/b2-1+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
S BIO Pte. Ltd. Curated by ChEMBL					Assay Description Inhibition of recombinant JAK3 using poly(Glu,Ala,Tyr) as substrate after 2 hrs by luminometric assay				J Med Chem 55: 2623-40 (2012) Article DOI: 10.1021/jm201454n BindingDB Entry DOI: 10.7270/Q2CC11RG
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