Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM50464513'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50464513 (CHEMBL4286900) Show SMILES Clc1cnc(Nc2ccc(OCC(=O)N3CCOCC3)c(Cl)c2)nc1Nc1cccc(NC(=O)C=C)c1 Show InChI InChI=1S/C25H24Cl2N6O4/c1-2-22(34)29-16-4-3-5-17(12-16)30-24-20(27)14-28-25(32-24)31-18-6-7-21(19(26)13-18)37-15-23(35)33-8-10-36-11-9-33/h2-7,12-14H,1,8-11,15H2,(H,29,34)(H2,28,30,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.30	n/a	n/a	n/a	n/a	n/a	n/a
The First Affiliated Hospital of Dalian Medical University Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal GST-tagged human JAK3 (781 to end residues) expressed in baculovirus infected Sf9 insect cells using Poly(4:1 Gl...				Eur J Med Chem 143: 1847-1857 (2018) Article DOI: 10.1016/j.ejmech.2017.10.080 BindingDB Entry DOI: 10.7270/Q22V2JR3
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