Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM50465339'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50465339 (CHEMBL4285076) Show SMILES [H][C@@]12CCc3cc(ccc3[C@@]1(C)CCC[C@@]2(CC(=O)OC)C(O)=O)C(C)(C)O |r| Show InChI InChI=1S/C22H30O5/c1-20(2,26)15-7-8-16-14(12-15)6-9-17-21(16,3)10-5-11-22(17,19(24)25)13-18(23)27-4/h7-8,12,17,26H,5-6,9-11,13H2,1-4H3,(H,24,25)/t17-,21-,22+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
Yunnan University Curated by ChEMBL					Assay Description Inhibition of JAK3 (unknown origin) by mobility shift assay				J Nat Prod 81: 998-1006 (2018) Article DOI: 10.1021/acs.jnatprod.7b01082 BindingDB Entry DOI: 10.7270/Q2P84FK3
					More data for this Ligand-Target Pair