Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM50465341'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50465341 (CHEMBL4289234) Show SMILES [H][C@@]12CCc3cc(O)ccc3[C@@]1(C)CCC[C@@]2(CC(=O)OC)C(O)=O |r| Show InChI InChI=1S/C19H24O5/c1-18-8-3-9-19(17(22)23,11-16(21)24-2)15(18)7-4-12-10-13(20)5-6-14(12)18/h5-6,10,15,20H,3-4,7-9,11H2,1-2H3,(H,22,23)/t15-,18-,19+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
Yunnan University Curated by ChEMBL					Assay Description Inhibition of JAK3 (unknown origin) by mobility shift assay				J Nat Prod 81: 998-1006 (2018) Article DOI: 10.1021/acs.jnatprod.7b01082 BindingDB Entry DOI: 10.7270/Q2P84FK3
					More data for this Ligand-Target Pair