Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM50530786'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50530786 (CHEMBL4448906) Show SMILES Fc1ccc2ncc(-c3ncc4[nH]c(=O)n([C@@H]5CCOc6c(F)cccc56)c4n3)n2c1 |r| Show InChI InChI=1S/C21H14F2N6O2/c22-11-4-5-17-24-9-16(28(17)10-11)19-25-8-14-20(27-19)29(21(30)26-14)15-6-7-31-18-12(15)2-1-3-13(18)23/h1-5,8-10,15H,6-7H2,(H,26,30)/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His-tagged JAK3 (795 to 1124 residues) expressed in Sf1 cells using PolyGT-Biotin as substrate measured af...				J Med Chem 62: 9045-9060 (2019) Article DOI: 10.1021/acs.jmedchem.9b00533 BindingDB Entry DOI: 10.7270/Q24Q7ZF5
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50530786 (CHEMBL4448906) Show SMILES Fc1ccc2ncc(-c3ncc4[nH]c(=O)n([C@@H]5CCOc6c(F)cccc56)c4n3)n2c1 |r| Show InChI InChI=1S/C21H14F2N6O2/c22-11-4-5-17-24-9-16(28(17)10-11)19-25-8-14-20(27-19)29(21(30)26-14)15-6-7-31-18-12(15)2-1-3-13(18)23/h1-5,8-10,15H,6-7H2,(H,26,30)/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His-tagged JAK3 (795 to 1124 residues) expressed in Sf1 cells using PolyGT-Biotin as substrate measured af...				J Med Chem 62: 9045-9060 (2019) Article DOI: 10.1021/acs.jmedchem.9b00533 BindingDB Entry DOI: 10.7270/Q24Q7ZF5
					More data for this Ligand-Target Pair