Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM50530788'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50530788 (CHEMBL4460058) Show SMILES C[C@H](c1ccc(F)cn1)n1c2nc(Nc3cc(Cl)c[nH]c3=O)ncc2[nH]c1=O |r| Show InChI InChI=1S/C17H13ClFN7O2/c1-8(11-3-2-10(19)6-20-11)26-14-13(24-17(26)28)7-22-16(25-14)23-12-4-9(18)5-21-15(12)27/h2-8H,1H3,(H,21,27)(H,24,28)(H,22,23,25)/t8-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His-tagged JAK3 (795 to 1124 residues) expressed in Sf1 cells using PolyGT-Biotin as substrate measured af...				J Med Chem 62: 9045-9060 (2019) Article DOI: 10.1021/acs.jmedchem.9b00533 BindingDB Entry DOI: 10.7270/Q24Q7ZF5
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50530788 (CHEMBL4460058) Show SMILES C[C@H](c1ccc(F)cn1)n1c2nc(Nc3cc(Cl)c[nH]c3=O)ncc2[nH]c1=O |r| Show InChI InChI=1S/C17H13ClFN7O2/c1-8(11-3-2-10(19)6-20-11)26-14-13(24-17(26)28)7-22-16(25-14)23-12-4-9(18)5-21-15(12)27/h2-8H,1H3,(H,21,27)(H,24,28)(H,22,23,25)/t8-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His-tagged JAK3 (795 to 1124 residues) expressed in Sf1 cells using PolyGT-Biotin as substrate measured af...				J Med Chem 62: 9045-9060 (2019) Article DOI: 10.1021/acs.jmedchem.9b00533 BindingDB Entry DOI: 10.7270/Q24Q7ZF5
					More data for this Ligand-Target Pair