Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM50544786'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50544786 (CHEMBL4637587) Show SMILES [H][C@@]12CN(C(=O)[C@]1(C#N)C1CC1)c1ccnc(Nc3cccc(CNC(=O)COC2)n3)c1 |r| Show InChI InChI=1S/C22H22N6O3/c23-13-22(14-4-5-14)15-10-28(21(22)30)17-6-7-24-19(8-17)27-18-3-1-2-16(26-18)9-25-20(29)12-31-11-15/h1-3,6-8,14-15H,4-5,9-12H2,(H,25,29)(H,24,26,27)/t15-,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of JAK3 (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.126963 BindingDB Entry DOI: 10.7270/Q24X5CCJ
					More data for this Ligand-Target Pair