Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM50557483'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50557483 (CHEMBL4782814) Show SMILES [H][C@]12C[C@]([H])(C[C@H](CC1)Nc1nc(Nc3cc(C)[nH]n3)cc3ncccc13)N2CCC#N |r,TLB:28:27:2:8.6.7.5| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	992	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human JAK3 assessed as phosphorylation level in presence of 1 mM ATP				Citation and Details Article DOI: 10.1016/j.bmcl.2021.127862 BindingDB Entry DOI: 10.7270/Q21V5JNK
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