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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lck' and Ligand = 'BDBM50112968'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50112968
PNG
(CHEMBL413761 | Phosphoric acid mono-{4-[(S)-2-acet...)
Show SMILES CC(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)N[C@H]1CCC(=O)N2CCC[C@H](N2C1=O)C(=O)NCc1ccccc1
Show InChI InChI=1S/C28H34N5O9P/c1-18(34)30-23(16-19-9-11-21(12-10-19)42-43(39,40)41)26(36)31-22-13-14-25(35)32-15-5-8-24(33(32)28(22)38)27(37)29-17-20-6-3-2-4-7-20/h2-4,6-7,9-12,22-24H,5,8,13-17H2,1H3,(H,29,37)(H,30,34)(H,31,36)(H2,39,40,41)/t22-,23-,24-/m0/s1
PDB

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PC cid
PC sid
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Similars
PubMed
n/an/a 1.50E+3n/an/an/an/an/an/a



Roche Products Limited

Curated by ChEMBL


Assay Description
Inhibitory activity towards p56 Lck tyrosine kinase SH2 domain using scintillation proximity assay (SPA)

Bioorg Med Chem Lett 12: 1365-9 (2002)


BindingDB Entry DOI: 10.7270/Q20002MH
More data for this
Ligand-Target Pair