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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lck' and Ligand = 'BDBM50112975'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50112975
PNG
(CHEMBL282111 | Phosphoric acid mono-(4-{(S)-2-acet...)
Show SMILES CC(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)N[C@H]1CCC(=O)N2CCC[C@H](N2C1=O)C(=O)NC1CCc2ccccc12
Show InChI InChI=1S/C30H36N5O9P/c1-18(36)31-25(17-19-8-11-21(12-9-19)44-45(41,42)43)28(38)33-24-14-15-27(37)34-16-4-7-26(35(34)30(24)40)29(39)32-23-13-10-20-5-2-3-6-22(20)23/h2-3,5-6,8-9,11-12,23-26H,4,7,10,13-17H2,1H3,(H,31,36)(H,32,39)(H,33,38)(H2,41,42,43)/t23?,24-,25-,26-/m0/s1
PDB

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PC cid
PC sid
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Similars
PubMed
n/an/a 1.20E+3n/an/an/an/an/an/a



Roche Products Limited

Curated by ChEMBL


Assay Description
Inhibitory activity towards p56 Lck tyrosine kinase SH2 domain using scintillation proximity assay (SPA)

Bioorg Med Chem Lett 12: 1365-9 (2002)


BindingDB Entry DOI: 10.7270/Q20002MH
More data for this
Ligand-Target Pair