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Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lck' and Ligand = 'BDBM50241732'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50241732
PNG
(CHEMBL4091764)
Show SMILES COc1ccc(cc1OC)-c1n[nH]c(NCc2c(F)cccc2Cl)n1
Show InChI InChI=1S/C17H16ClFN4O2/c1-24-14-7-6-10(8-15(14)25-2)16-21-17(23-22-16)20-9-11-12(18)4-3-5-13(11)19/h3-8H,9H2,1-2H3,(H2,20,21,22,23)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 18n/an/an/an/an/an/a



National Institute of Biological Sciences, Beijing

Curated by ChEMBL


Assay Description
Inhibition of ADP-induced platelet aggregation in human platelet-rich plasma

J Med Chem 60: 8552-8564 (2017)


Article DOI: 10.1021/acs.jmedchem.7b01075
BindingDB Entry DOI: 10.7270/Q25X2C34
More data for this
Ligand-Target Pair