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Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lck' and Ligand = 'BDBM50291085'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50291085
PNG
((3,4,5-Trimethoxy-phenyl)-(6,7,8-trimethoxy-quinaz...)
Show SMILES COc1cc(Nc2ncnc3c(OC)c(OC)c(OC)cc23)cc(OC)c1OC
Show InChI InChI=1S/C20H23N3O6/c1-24-13-7-11(8-14(25-2)17(13)27-4)23-20-12-9-15(26-3)18(28-5)19(29-6)16(12)21-10-22-20/h7-10H,1-6H3,(H,21,22,23)
PDB

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PC sid
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Similars
Article
n/an/a>1.00E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of p56 Lck tyrosine kinase in Jurkat cells where p56lck autophosphorylation is inhibited.

Bioorg Med Chem Lett 7: 417-420 (1997)


Article DOI: 10.1016/S0960-894X(97)00034-6
BindingDB Entry DOI: 10.7270/Q2J966VN
More data for this
Ligand-Target Pair