Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Mer' and Ligand = 'BDBM497260'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM497260 ((4-(7-((1R,4S)-4- hydroxycyclohexyl)-2- (((S)-pent...) Show SMILES CCC[C@H](C)Nc1ncc2c(cn([C@H]3CC[C@H](O)CC3)c2n1)C1CCN(CC1)C(=O)c1ccncc1 |r,wU:13.12,wD:3.3,16.16,(-8.58,-2.22,;-7.25,-1.45,;-5.92,-2.22,;-4.58,-1.45,;-4.58,.09,;-3.25,-2.22,;-1.91,-1.45,;-1.91,.09,;-.58,.86,;.75,.09,;2.22,.57,;3.12,-.68,;2.22,-1.92,;2.69,-3.39,;4.2,-3.71,;4.68,-5.17,;3.64,-6.32,;4.12,-7.78,;2.14,-6,;1.66,-4.53,;.75,-1.45,;-.58,-2.22,;2.69,2.03,;4.2,2.35,;4.68,3.82,;3.64,4.96,;2.14,4.64,;1.66,3.18,;4.12,6.43,;3.39,7.78,;5.61,6.03,;6.01,4.54,;7.49,4.14,;8.58,5.23,;8.18,6.72,;6.7,7.12,)| Show InChI InChI=1S/C28H38N6O2/c1-3-4-19(2)31-28-30-17-24-25(18-34(26(24)32-28)22-5-7-23(35)8-6-22)20-11-15-33(16-12-20)27(36)21-9-13-29-14-10-21/h9-10,13-14,17-20,22-23,35H,3-8,11-12,15-16H2,1-2H3,(H,30,31,32)/t19-,22-,23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of MERTK (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113534 BindingDB Entry DOI: 10.7270/Q2M90DGJ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM497260 ((4-(7-((1R,4S)-4- hydroxycyclohexyl)-2- (((S)-pent...) Show SMILES CCC[C@H](C)Nc1ncc2c(cn([C@H]3CC[C@H](O)CC3)c2n1)C1CCN(CC1)C(=O)c1ccncc1 |r,wU:13.12,wD:3.3,16.16,(-8.58,-2.22,;-7.25,-1.45,;-5.92,-2.22,;-4.58,-1.45,;-4.58,.09,;-3.25,-2.22,;-1.91,-1.45,;-1.91,.09,;-.58,.86,;.75,.09,;2.22,.57,;3.12,-.68,;2.22,-1.92,;2.69,-3.39,;4.2,-3.71,;4.68,-5.17,;3.64,-6.32,;4.12,-7.78,;2.14,-6,;1.66,-4.53,;.75,-1.45,;-.58,-2.22,;2.69,2.03,;4.2,2.35,;4.68,3.82,;3.64,4.96,;2.14,4.64,;1.66,3.18,;4.12,6.43,;3.39,7.78,;5.61,6.03,;6.01,4.54,;7.49,4.14,;8.58,5.23,;8.18,6.72,;6.7,7.12,)| Show InChI InChI=1S/C28H38N6O2/c1-3-4-19(2)31-28-30-17-24-25(18-34(26(24)32-28)22-5-7-23(35)8-6-22)20-11-15-33(16-12-20)27(36)21-9-13-29-14-10-21/h9-10,13-14,17-20,22-23,35H,3-8,11-12,15-16H2,1-2H3,(H,30,31,32)/t19-,22-,23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<3	n/a	n/a	n/a	n/a	n/a	n/a
The University of North Carolina at Chapel Hill US Patent					Assay Description Activity Against Mer Tyrosine Kinase.				US Patent US11001586 (2021) BindingDB Entry DOI: 10.7270/Q2F47S8S
					More data for this Ligand-Target Pair