Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Mer' and Ligand = 'BDBM50444269'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50444269 (CHEMBL3093629) Show SMILES OCCCNc1ncc(C(=O)Nc2ccc(cc2)S(=O)(=O)N2CCOCC2)c(N[C@H]2CC[C@H](O)CC2)n1 |r,wU:29.30,wD:32.34,(24.63,-35.11,;25.96,-34.34,;27.3,-35.11,;28.63,-34.34,;29.96,-35.12,;31.3,-34.35,;32.63,-35.12,;33.97,-34.35,;33.96,-32.8,;35.29,-32.02,;35.29,-30.48,;36.63,-32.79,;37.96,-32.01,;39.29,-32.78,;40.62,-32.01,;40.62,-30.47,;39.27,-29.7,;37.95,-30.48,;41.95,-29.68,;41.17,-28.35,;42.72,-28.34,;43.28,-30.45,;43.28,-31.99,;44.61,-32.75,;45.94,-31.98,;45.94,-30.44,;44.6,-29.67,;32.63,-32.03,;32.62,-30.49,;31.29,-29.73,;29.96,-30.5,;28.62,-29.72,;28.62,-28.18,;27.29,-27.41,;29.96,-27.41,;31.29,-28.18,;31.3,-32.8,)| Show InChI InChI=1S/C24H34N6O6S/c31-13-1-10-25-24-26-16-21(22(29-24)27-17-2-6-19(32)7-3-17)23(33)28-18-4-8-20(9-5-18)37(34,35)30-11-14-36-15-12-30/h4-5,8-9,16-17,19,31-32H,1-3,6-7,10-15H2,(H,28,33)(H2,25,26,27,29)/t17-,19-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Eshelman School of Pharmacy�Department of Pharmacology�Lineberger Compreh Curated by ChEMBL					Assay Description Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9693-700 (2014) Article DOI: 10.1021/jm4013888 BindingDB Entry DOI: 10.7270/Q21G0NQ1
					More data for this Ligand-Target Pair