Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Mer' and Ligand = 'BDBM50444271'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50444271 (CHEMBL3093627) Show SMILES O[C@H]1CC[C@@H](CC1)Nc1nc(NCCC2CC2)ncc1C(=O)Nc1ccc(cc1)S(=O)(=O)N1CCOCC1 |r,wU:4.7,wD:1.0,(51.32,-15.73,;52.65,-16.5,;52.65,-18.04,;53.99,-18.82,;55.31,-18.05,;55.31,-16.5,;53.98,-15.73,;56.65,-18.81,;56.65,-20.35,;55.32,-21.12,;55.32,-22.67,;53.99,-23.44,;52.65,-22.66,;51.32,-23.43,;49.99,-22.66,;49.22,-21.33,;48.45,-22.66,;56.66,-23.44,;57.99,-22.67,;57.99,-21.12,;59.32,-20.34,;59.31,-18.8,;60.65,-21.11,;61.99,-20.33,;63.32,-21.1,;64.65,-20.33,;64.64,-18.79,;63.3,-18.02,;61.97,-18.8,;65.97,-18,;65.2,-16.67,;66.74,-16.66,;67.31,-18.77,;67.31,-20.31,;68.64,-21.07,;69.97,-20.3,;69.97,-18.76,;68.63,-17.99,)| Show InChI InChI=1S/C26H36N6O5S/c33-21-7-3-19(4-8-21)29-24-23(17-28-26(31-24)27-12-11-18-1-2-18)25(34)30-20-5-9-22(10-6-20)38(35,36)32-13-15-37-16-14-32/h5-6,9-10,17-19,21,33H,1-4,7-8,11-16H2,(H,30,34)(H2,27,28,29,31)/t19-,21-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.30	n/a	n/a	n/a	n/a	n/a	n/a
Eshelman School of Pharmacy�Department of Pharmacology�Lineberger Compreh Curated by ChEMBL					Assay Description Inhibition of Mer kinase (unknown origin) using 5-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluidic capillary electrophoresis assay				J Med Chem 56: 9693-700 (2014) Article DOI: 10.1021/jm4013888 BindingDB Entry DOI: 10.7270/Q21G0NQ1
					More data for this Ligand-Target Pair