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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Mer' and Ligand = 'BDBM50466393'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase Mer


(Homo sapiens (Human))		BDBM50466393
PNG
(CHEMBL4277499)
Show SMILES Fc1ccc(cc1)-n1cccc(C(=O)Nc2ccc(Oc3ccnc4[nH]cnc34)c(F)c2)c1=O
Show InChI InChI=1S/C24H15F2N5O3/c25-14-3-6-16(7-4-14)31-11-1-2-17(24(31)33)23(32)30-15-5-8-19(18(26)12-15)34-20-9-10-27-22-21(20)28-13-29-22/h1-13H,(H,30,32)(H,27,28,29)
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n/an/a 90n/an/an/an/an/an/a



PSL Research University

Curated by ChEMBL


Assay Description
Inhibition of recombinant GST-tagged human Mer (578 to 872 residues) cytoplasmic domain expressed in Baculovirus system using poly (Glu-Ala-Tyr) pept...

Bioorg Med Chem 26: 5510-5530 (2018)


Article DOI: 10.1016/j.bmc.2018.09.031
BindingDB Entry DOI: 10.7270/Q27S7RGR
More data for this
Ligand-Target Pair