Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Mer' and Ligand = 'BDBM50469350'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50469350 (CHEMBL4284846) Show SMILES CCC[C@H](C)Nc1ncc2c(cn([C@H]3CC[C@H](O)CC3)c2n1)-c1ccnc(c1)C(=O)OC |r,wU:13.12,wD:16.16,3.3,(1.51,-9.85,;2.84,-9.08,;4.18,-9.86,;5.51,-9.09,;5.51,-7.55,;6.84,-9.86,;8.18,-9.09,;8.18,-7.54,;9.51,-6.77,;10.84,-7.54,;12.32,-7.06,;13.23,-8.31,;12.32,-9.57,;13.07,-10.91,;14.6,-10.93,;15.35,-12.29,;14.55,-13.61,;15.29,-14.96,;13.01,-13.57,;12.27,-12.23,;10.84,-9.09,;9.51,-9.86,;13.03,-5.69,;12.21,-4.4,;12.91,-3.04,;14.46,-2.97,;15.28,-4.27,;14.57,-5.63,;16.82,-4.21,;17.54,-2.84,;17.65,-5.51,;16.93,-6.87,)| Show InChI InChI=1S/C24H31N5O3/c1-4-5-15(2)27-24-26-13-19-20(16-10-11-25-21(12-16)23(31)32-3)14-29(22(19)28-24)17-6-8-18(30)9-7-17/h10-15,17-18,30H,4-9H2,1-3H3,(H,26,27,28)/t15-,17-,18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
UNC Eshelman School of Pharmacy Curated by ChEMBL					Assay Description Inhibition of MERTK (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assay				J Med Chem 61: 10242-10254 (2018) Article DOI: 10.1021/acs.jmedchem.8b01229 BindingDB Entry DOI: 10.7270/Q2K076ZK
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