Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Mer' and Ligand = 'BDBM50469370'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM50469370 (CHEMBL4291202) Show SMILES CCC[C@H](C)Nc1ncc2c(cn([C@H]3CC[C@H](O)CC3)c2n1)-c1ccc(CN2CCOCC2)cc1 |r,wU:13.12,wD:16.16,3.3,(-2.13,-9.06,;-.79,-8.29,;.55,-9.06,;1.88,-8.29,;1.89,-6.75,;3.22,-9.06,;4.55,-8.29,;4.55,-6.75,;5.88,-5.98,;7.22,-6.74,;8.69,-6.26,;9.6,-7.52,;8.69,-8.77,;9.44,-10.11,;10.97,-10.14,;11.72,-11.49,;10.92,-12.81,;11.66,-14.16,;9.38,-12.77,;8.64,-11.43,;7.22,-8.29,;5.88,-9.06,;9.4,-4.9,;10.94,-4.84,;11.66,-3.48,;10.83,-2.18,;11.54,-.81,;13.08,-.74,;13.9,-2.05,;15.43,-1.99,;16.15,-.63,;15.33,.69,;13.79,.63,;9.28,-2.24,;8.58,-3.61,)| Show InChI InChI=1S/C28H39N5O2/c1-3-4-20(2)30-28-29-17-25-26(19-33(27(25)31-28)23-9-11-24(34)12-10-23)22-7-5-21(6-8-22)18-32-13-15-35-16-14-32/h5-8,17,19-20,23-24,34H,3-4,9-16,18H2,1-2H3,(H,29,30,31)/t20-,23-,24-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
UNC Eshelman School of Pharmacy Curated by ChEMBL					Assay Description Inhibition of MERTK (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assay				J Med Chem 61: 10242-10254 (2018) Article DOI: 10.1021/acs.jmedchem.8b01229 BindingDB Entry DOI: 10.7270/Q2K076ZK
					More data for this Ligand-Target Pair