Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM26402'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM26402 (5-amino-7-[(3,5-dimethoxyphenyl)amino]imidazo[1,2-...) Show SMILES COc1cc(Nc2nc(N)n3ccnc3c2C(N)=O)cc(OC)c1 Show InChI InChI=1S/C15H16N6O3/c1-23-9-5-8(6-10(7-9)24-2)19-13-11(12(16)22)14-18-3-4-21(14)15(17)20-13/h3-7,19H,1-2H3,(H2,16,22)(H2,17,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Company Ltd Curated by ChEMBL					Assay Description Inhibition of human Syk expressed in Sf9 cells				Bioorg Med Chem 16: 9247-60 (2008) Article DOI: 10.1016/j.bmc.2008.09.015 BindingDB Entry DOI: 10.7270/Q2GM887N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM26402 (5-amino-7-[(3,5-dimethoxyphenyl)amino]imidazo[1,2-...) Show SMILES COc1cc(Nc2nc(N)n3ccnc3c2C(N)=O)cc(OC)c1 Show InChI InChI=1S/C15H16N6O3/c1-23-9-5-8(6-10(7-9)24-2)19-13-11(12(16)22)14-18-3-4-21(14)15(17)20-13/h3-7,19H,1-2H3,(H2,16,22)(H2,17,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Company					Assay Description A coupled spectrophotometric assay was used, wherein ADP generated by Syk kinase was converted to ATP by pyruvate kinase (PK), with concomitant produ...				Bioorg Med Chem 17: 284-94 (2009) Article DOI: 10.1016/j.bmc.2008.10.070 BindingDB Entry DOI: 10.7270/Q2FQ9TXB
					More data for this Ligand-Target Pair