Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM26427'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM26427 (5-({[4-(carbamoylmethyl)phenyl]methyl}amino)-7-[(3...) Show SMILES COc1cc(Nc2nc(NCc3ccc(CC(N)=O)cc3)n3ccnc3c2C(N)=O)cc(OC)c1 Show InChI InChI=1S/C24H25N7O4/c1-34-17-10-16(11-18(12-17)35-2)29-22-20(21(26)33)23-27-7-8-31(23)24(30-22)28-13-15-5-3-14(4-6-15)9-19(25)32/h3-8,10-12,29H,9,13H2,1-2H3,(H2,25,32)(H2,26,33)(H,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Company					Assay Description A coupled spectrophotometric assay was used, wherein ADP generated by Syk kinase was converted to ATP by pyruvate kinase (PK), with concomitant produ...				Bioorg Med Chem 17: 284-94 (2009) Article DOI: 10.1016/j.bmc.2008.10.070 BindingDB Entry DOI: 10.7270/Q2FQ9TXB
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